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Researchers Propose “Brain Observatory” Neurotechnology Centers

Scanning of a human brain by X-rays. 3d image.Researchers are calling for a coordinated national network of neurotechnology centers or “brain observatories.” As proposed in an Opinion paper published in the Neuron journal, the observatories would augment the NiH BRAIN Initiative involving more than 100 laboratories in the United States has already made progress in establishing large-scale neuroscience goals and developing shared tools.

It is our view that the technological challenges that must be surmounted are sufficiently complex that they are beyond the reach of single-investigator efforts; we believe they can only be surmounted through highly coordinated, multi-investigator, cross-disciplinary efforts,” the authors write. “These centers could be similar to existing astronomical observatories, where large-scale technology development and deployment is carried out in a centralized fashion, and where facilities are then shared by the entire community.”

The authors outline four primary areas of the BRAIN initiative that are critically dependent on new technology that would be unlikely to be quickly realized outside of a center-based framework. These include connectomics–the systematic reconstruction of neural circuits–neural nanoprobe systems, new resonance imaging technologies, and computational data mining. Each of these requires platforms that are expensive to acquire, implement, and maintain, and, if only hosted in one lab, would affect scientific reproducibility and robustness.

We believe that the early stage of the BRAIN initiative has laid the groundwork for the next critical stages: enabling the development of integrated neurotechnology systems and, subsequently, the broad dissemination of newly created tools,” the authors write. “There is tremendous opportunity for rapid progress in the four areas mentioned above if the BRAIN Initiative expands beyond its current portfolio of single- and few-investigator projects. These centers would unite and synergize the hundreds of individual laboratories now funded by the BRAIN Initiative.”

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