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Podcast: Combining Cryo-electron Microscopy with Supercomputer Simulation

Scientists have taken the closest look yet at molecule-sized machinery called the human preinitiation complex. It basically opens up DNA so that genes can be copied and turned into proteins. The science team formed from Northwestern University, Berkeley National Laboratory, Georgia State University, and UC Berkeley. They used a cutting-edge technique called cryo-electron microscopy and combined it with supercomputer analysis. They published their results May of 2016 in the journal Nature.

Video: For Precision Medicine, HPC Matters at SC16

In this video from SC16, Steve Conway from IDC moderates a panel discussion on Precision Medicine. “Recently, DOE Secretary Moniz, VA Secretary MacDonald, NCI Director Lowy and the GSK CEO Andrew Witty announced that the Nation’s leading supercomputers would be applied to the challenge of the Cancer Moonshot initiative. This partnership of nontraditional groups, collectively see the path to unraveling the complexities of cancer through the power of new machines, operating systems, and applications that leverage simulations, data science and artificial intelligence to accelerate bringing precision oncology to the patients that are waiting. This initiative is one of many research efforts in the race to solve some of our most challenging medical problems.”

Video: Jen-Hsun Huang Keynote from the Nvidia Booth at SC16

Watch this video of Nvidia CEO Jen-Hsun Huang’s talk from SC16 in Salt Lake City. Can’t make it to the show? Tune in right here on insideHPC to watch Nvidia talks all this week. “See how other leaders in the field are advancing computational science across domains, get free hands-on training with the newest GPU-accelerated solutions, and connect with NVIDIA experts.”

It’s Here: The Print ‘n Fly Guide to SC16 in Salt Lake City

At insideHPC, are very pleased to publish the Print ‘n Fly Guide to SC16 in Salt Lake City. We designed this Guide to be an in-flight magazine custom tailored for your journey to SC16 — the world’s largest gathering of high performance computing professionals. “Inside this guide you will find technical features on supercomputing, HPC interconnects, and the latest developments on the road to exascale. It also has great recommendations on food, entertainment, and transportation in SLC.”

Simulating Jellyfish Blooms to Protect Coastal Power Stations

Scientists at the University of Bristol are working with the energy industry to develop an ‘early warning tool’ to predict jellyfish blooms that can cause serious problems by clogging the water intakes of coastal power plants. “To achieve this we will be translating previous research using a state-of-the-art marine dispersal modeling system to simulate the transport of jellyfish blooms by ocean currents, incorporating specific biological behaviors of jellyfish.”

UK Met Office Research Simulations Predict European Winter One Year Ahead

In a paper published today in Nature Geoscience, scientists at the Met Office have demonstrated significant advances in predicting up to one year ahead the phases of the North Atlantic Oscillation (NAO), which drives European and North American winter variability. The NAO – a large-scale gradient in air pressure measured between low pressure around Iceland and high pressure around the Azores – is the primary driver of winter climate variability for Europe.

The High Performance Virtual Computer for Graphics-Intensive Applications

Many industries deploy graphics-intensive applications on single user workstations with individual GPU resources. For those who have switched to a virtualization based environment, many of the legacy desktop virtualization platforms can’t support high end GPUs or multiple GPU configurations. Together with partners like Cisco and One Stop Systems, a London-based tech start-up ebb3 has created the High Performance Virtual Computer (HPVC) to tackle this issue with the aim of creating the fastest performing solution in the world.

PASC17 Conference to Focus on HPC & Precision Medicine

Today the PASC17 Conference announced a track focused on Precision Medicine as Special Topic for Emerging Domains. “Precision medicine, also referred to as personalized medicine, is an emerging domain that is adding tremendous value to the study of life sciences and medical treatment. The requirements that it has for rapid – and secure – processing, analysis and management of vast quantities of data in a wide range of different medical environments make precision medicine ideally suited to high performance computing.”

Supercomputing Tornadogenesis

“We’re trying to make high resolution simulations of super cell storms, or tornadoes,” McGovern said. “What we get with the simulations are the fundamental variables of whatever our resolution is — we’ve been doing 100 meter x 100 meter cubes — there’s no way you can get that kind of data without doing simulations. We’re getting the fundamental variables like pressure, temperature and wind, and we’re doing that for a lot of storms, some of which will generate tornadoes and some that won’t. The idea is to do data mining and visualization to figure out what the difference is between the two.”

Dell Powers RENCI Supercomputer Tracking Hurricane Matthew

RENCI’s Dell-powered supercomputer is working overtime to model the storm surge that Hurricane Matthew could bring to communities along the Eastern Seaboard. Named Hatteras, the 150-node M610 Dell cluster runs the ADCIRC storm surge model every six hours when a hurricane is active. “We are working on doing storm surge predictions the same way that meteorologists develop predictions for rain and wind speeds.”