httpv://www.youtube.com/watch?v=rIcXmU7XPCQ
In this video, San Diego Supercomputer Center Director Michael Norman presents Simulating the 4% Universe: Hydro-cosmology Simulations and Data Analysis. Recorded at the 2012 International Summer School on AstroComputing.
All of the rest of the HIPACC/ISSAC videos are also online, many of which discuss HPC topics in Astronomy:
http://www.youtube.com/playlist?list=PL1EC2A919AEB24215&feature=plcp (week 1)
http://www.youtube.com/playlist?list=PL3E8B2C677BC87DF8&feature=plcp (week 2)