In this video from SC16, Garima Kochhar from Dell EMC describes the CryoEM Demo on the Dell PowerEdge C6320 rack server powered by Intel Xeon and Intel Xeon Phi.
“This demo presents performance results for the 2D alignment and 2D classification phases of the Cryo-electron microscopy (Cryo-EM) data processing workflow using the new Intel Knights Landing architecture, and compares these results to the performance of the Intel Xeon E5-2600 v4 family.”
Cryo-EM allows molecular samples to be studied in near-native states and down to nearly atomic resolutions. Studying the 3D structure of these biological specimens can lead to new insights into their functioning and interactions, especially with proteins and nucleic acids, and allows structural biologists to examine how alterations in their structures affect their functions. This information can be used in system biology research to understand the cell signaling network which is part of a complex communication system. This communication system controls fundamental cell activities and actions to maintain normal cell homeostasis. Errors in the cellular signaling process can lead to diseases such as cancer, autoimmune disorders, and diabetes. Studying the functioning of the proteins responsible for an illness enables a biologist to develop specific drugs that can interact with the protein effectively, thus improving the efficacy of treatment.”
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