Software-Defined Networking (SDN) is a concept that has emerged in recent years to decouple network control and forwarding functions. The one network type that does not require special effort to adjust it to the computational needs of high-performance computing, deep learning or any other data intensive application is InfiniBand. In this guest article, Mellanox Technologies’ Gilad Shainer and Eitan Zahavi explore Infiniband networks and the benefits and potential of software-defined networking.