“The basic idea of deep learning is to automatically learn to represent data in multiple layers of increasing abstraction, thus helping to discover intricate structure in large datasets. NVIDIA has invested in SaturnV, a large GPU-accelerated cluster, (#28 on the November 2016 Top500 list) to support internal machine learning projects. After an introduction to deep learning on GPUs, we will address a selection of open questions programmers and users may face when using deep learning for their work on these clusters.”