The term next generation sequencing (NGS) is really a misnomer. NGS implies a single methodology, but the fact is that over the past 10 to 15 years there have been multiple generations and the end is nowhere in sight. Technological advances in the field are continuing to emerge at a record setting pace.
Parallel Storage Solutions for Better Performance
August 31, 2016 by Leave a Comment
Using high performance parallel storage solutions, geologists and researchers can now incorporate larger data sets and execute more seismic and reservoir simulations faster than ever before, enabling higher fidelity geological analysis and significantly reduced exploration risk. With high costs of exploration, oil and gas companies are increasingly turning to high performance DDN storage solutions to eliminate I/O bottlenecks, minimize risk and costs, while delivering a larger number of higher fidelity simulations in same time as traditional storage architectures.
Weather and Climate Forecasting
August 31, 2016 by Leave a Comment
In the pantheon of HPC grand challenges, weather forecasting and long-term climate simulation rank right up there with the most complex and com- putationally demanding problems in astrophysics, aeronautics, fusion power, exotic materials,and earthquake prediction, to name just a few. Modern weather prediction requires cooperation in the collection of observed data and sharing of forecasts output among all nations, a collabora- tion that has been ongoing for decades. This data is used to simulate effects on a range of scales— from events, such as the path of tornados, that change from minute to minute and move over distances measured in meters, to turnover of water layers in the ocean, a process that is measured in decades or even hundreds of years, and spans thousands of miles.
Genomics High Performance Computing Guide
August 31, 2016 by Leave a Comment
There are times when a convergence of technologies happens that can benefit a very large number of humans in order to improve their well-being. A number of technological innovations are coming together that can greatly enhance the recovery from life-threatening illnesses and prolong and improve the quality of life. With a combination of faster and more accurate genomics sequencing, faster computer systems and new algorithms, the movement of discovering what medicine will work best on individual patients has moved from research institutions to bedside doctors. Physicians and other healthcare providers now have better, faster, and more accurate tools and data to determine optimal treatment plans based on more patient data. This is especially true for pediatric cancer patients. These fast-moving technologies have become the center of a national effort to help millions of people overcome certain diseases.
Life Sciences: IBM Computing Solutions
August 31, 2016 by Leave a Comment
Whether engaged in genome sequencing, drug design, product analysis or risk management, life sciences research teams need high-performance technical environments with the ability to process massive amounts of data and support increasingly sophisticated simulations and analyses. Organizations helping to find causes and cures for diseases need speed, agility and control across the clinical development lifecycle to increase productivity, foster innovation and compete more effectively.
Metadata Used in Science
August 31, 2016 by Leave a Comment
Metadata is the key to keeping track of all this unstructured scientific data. It is “data about data.” In the case of scientific data, it is structured data (written in a prescribed schema or order) that describes what the data is, how it was derived, and where it is located.
MIPT in Moscow Develops New Method of Calculating Protein Interaction
July 25, 2016 by
Biologists and mathematicians from the Moscow Institute of Physics and Technology (MIPT) have accelerated the rate at which a computer can predict the structure of protein complexes in a cell. “The new method enables us to model the interaction of proteins at the genome level. This will give us a better understanding of how our cells function and may enable drug development for diseases caused by ‘incorrect’ protein interactions,” commented Dima Kozakov, a professor at Stony Brook and adjunct professor at MIPT.
Gordon Supercomputer Aids Search for New Antibiotics
January 5, 2016 by
Researchers using the Gordon Supercomputer at SDSC have identified a class of possible antibiotics with the potential to disable previously drug-resistant bacteria. In essence, these new agents were found to attack the bacteria along two fronts: its external lipid cellular wall and its internal factory responsible for generating cellular energy in the form of adenosine triphosphate or ATP.
insideHPC Guide to Personalized Medicine & Genomics
January 5, 2016 by Leave a Comment
The insideHPC Guide to Personalized Medicine and Genomics explains how genomics will accelerate personalized medicine including several case studies.
How Can HPC Best Help Pharma R&D?
December 2, 2015 by
“The challenges facing informatics systems in the pharmaceutical industry’s R&D laboratories are changing. The number of large-scale computational problems in the life sciences is growing and they will need more high-performance solutions than their predecessors. But the response has to be nuanced: HPC is not a cure-all for the computational problems of pharma R&D. Some applications are better suited to the use of HPC than others and its deployment needs to be considered right at the beginning of experimental design.”
