In this Let’s Talk Exascale podcast, Kathy Yelick and Lenny Oliker from LBNL describe how the ExaBiome project is developing computational tools to analyze microbial species—bacteria or viruses that typically live in communities of hundreds of different species. “Pushing past the traditional shared-memory-system approach, the ExaBiome team has developed efficient distributed memory implementations and analyzed some of the largest datasets in the metagenomics community.”